Selective hypersensitivity to bradykinin in salivary glands with ligated ducts
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Transferring genes to salivary glands.
This review provides a brief description of gene transfer studies using salivary glands as the target tissue. The aggregate results demonstrate the potential clinical value of this methodological approach for managing several conditions lacking fully satisfactory conventional treatments. Routine clinical applications are still seven to ten years away, primarily because of the need for improved ...
متن کاملClcn2 encodes the hyperpolarization-activated chloride channel in the ducts of mouse salivary glands.
Transepithelial Cl(-) transport in salivary gland ducts is a major component of the ion reabsorption process, the final stage of saliva production. It was previously demonstrated that a Cl(-) current with the biophysical properties of ClC-2 channels dominates the Cl(-) conductance of unstimulated granular duct cells in the mouse submandibular gland. This inward-rectifying Cl(-) current is activ...
متن کاملSalivary Glands
Mod&r, Lavstedt, and Ahlund studied the oral health effects of smoking and snuff use in 232 Swedish school children ages 13 to 14 years (119 boys and 113 girls) (36). Thirteen (11 percent) of the boys used snuff. The children were interviewed regarding their tobacco and toothbrushing habits, and examin ers (blind to the interview results) clinically assessed the degree of gingival mflammation, ...
متن کاملSalivary Glands
Saliva plays an essential role in maintaining oral health. Alterations in salivary function lead to compromise of oral tissues and functions and have a large impact on a patient’s quality of life. Reductions in salivary flow most commonly manifest as symptoms of oral dryness. This subjective complaint of dry mouth is termed xerostomia, whereas objective alterations in salivary performance, quan...
متن کاملbiotin in salivary glands
Aims: To detect the presence of human herpes virus 6 (HHV6) and endogenous biotin in paraffin wax embedded and frozen salivary glands. Methods: Two stage indirect and streptavidin-biotin immunoperoxidase techniques were used to visualise the antigens. Results: HHV6 could not be shown in any of the tissues. However, considerable endogenous biotin antigenicity was detected in the glandular elemen...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1970
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1970.sp009264